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Objective To analyze the epidemiological characteristics and influence factors of human brucellosis in Jilin Province and provide scientific basis for enacting prevention and control strategy to brucellosis in the new period.Methods Descriptive epidemiological methods were used to analyze the epidemiological characteristics (regional distribution,time distribution,population distribution,etc.),influencing factors (risk factors,protective measures and epidemic prevention),epidemic links,detection methods,clinical stages and prognosis of reported brucellosis cases in Jilin Province from 2011 to 2017.Results From 2011 to 2017,12 116 cases of brucellosis were reported in Jilin Province,with an average incidence of 6.30/100 000.The annual incidence rates were 7.51/100 000,7.11/100 000,7.36/100 000,6.58/100 000,5.90/100 000,5.38/100 000 and 4.24/100 000,respectively.The reported cases were mainly distributed in Songyuan City and Baicheng City,accounting for 73.29％ (8 880/12 116) of the total number of reported cases;the time was from January to July,and the peak was from March to May.The age of onset ranged from 20 to 70 years old,mainly in young and middle-aged adults,accounting for 95.86％ (11 615/12 116) of the total number of reported cases.The following factors were studied:to take protective measures rate,human and animal mixed live,the same water source,colony house housing disinfection,manage abortion,buy animal quarantine,raise livestock immunity,and the proportion of these factors in each year was 24.38％ to 43.33％,3.11％ to 17.35％,63.68％ to 76.58％,25.40％ to 35.07％,21.66％ to 34.49％,9.32％ to 29.66％,26.09％ to 45.45％,respectively.The main infection source was sick sheep,accounting for 96.72％ (11 718/12 116).Skin mucosa was the main route of transmission,followed by digestive tract,accounting for 61.55％ (7 458/12 116) and 34.17％ (4 140/12 116),respectively.The main transmission factors were apoblema and flying dust,accounting for 55.68％ (6 746/12 116) and 35.62％ (4 316/12 116),respectively.The number of reported cases of brucellosis was 90.55％ (10 971/12 116) through passive monitoring.The clinical stage was mostly acute,accounting for 92.01％ (11 148/12 116).Healing and improvement accounted for 60.80％ (7 367/12 116) and 37.93％ (4 596/12 116),respectively.Conclusions Brucellosis has dropped slightly in Jilin Province in 2011-2017,but remains high;the epidemic situation is still grim.We should further strengthen monitoring,health education and health promotion,team construction,in order to effectively control the occurrence of human brucellosis.
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Objective To discuss the clinical value of improved percutaneous lung biopsy under CT guidance.Methods Reviewed the clinical data of 80 cases of improved percutaneous lung biopsy under CT guidance,which were confirmed by surgery or pathology.When took the operation,18 G semi-automatic cutting biopsy needle (made in American Cook's company) was used to improve the ways of positioning scan,two-step method of insert the needle,and the cutting technique of coaxial in each direction.Results All of the 80 patients were successfully completed pathological biopsy,successful rate was 100.0％ (80/80),and diagnosis rate was 98.8％ (79/80),incidence of complication was 10.0 ％ (8/80),all of these patients were recovered after treatment 2-5 d.Conclusion The method of improved percutaneous lung biopsy under CT guidance is safe,effective,simple and practical,which has high successful rate and low complication rate,the generalizability is certain.
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BACKGROUND: Injectable artificial bone composite has been reported to consider as a moulding filler of vertebrae at the histology level; however, the therapeutic effect needs to be further studied at the level of axial pressure capacity. OBJECTIVE: To explore the axial pressure capacity of dogs with thoracolumbar fractures treated by injectable artificial bone composite. DESIGN, TIME AND SETTING: A randomized controlled animal experiment was performed at the Animal Laboratory of Shenzhen Longgang Central Hospital from September 2008 to January 2009. MATERIALS: Type I and type II vertebral pedicle screw systems were provided by Tianjin Zhengtian Medical Device Company Limited; injectable artificial bone composite, which was made of coral-hydroxylapatite compound, recombinant human bone morphogenetic protein-2 (Academy of Military Medical Sciences), and 2% chitosan solution (the Second Military Medical University of Chinese PLA and Shanghai Qisheng Biomaterials Institute), was manufactured according to the methods provided by Yin et al. METHODS: A total of 20 1-year-old healthy dogs were randomly divided into treatment and control groups with 10 dogs in each group. The model of those dogs with thoracolumbar fractures was made by imitating falling accidents; thereafter, the dogs in the treatment group were treated with vertebral pedicle screw system internal fixation and vertebroplasty by filling the injured vertebrae with injectable artificial bones. The control group was treated with vertebral pedicle screw system internal fixation alone. MAIN OUTCOME MEASURES: The maximum pressure intensity of injured vertebra, upper and lower vertebra at vertebral body center was detected using micro-computer pressure testing system after three months. RESULTS: The maximum pressure intensity at vertebral body center was not significant differences in the treatment group (100% cases) between injured vertebral body and its neighboring vertebral body, and axial loading was recovered. While that of 60% cases in the control group was significantly different (P